KMID : 0359920070260050630
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Korean Journal of Nephrology 2007 Volume.26 No. 5 p.630 ~ p.633
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A Case of IgA Nephropathy Associated with Leptospirosis
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Shin HoSik
Lee Sang-Eun Lee Sei-Won Chung Byung-Ha Hwang Tae-Jun Kwak Jin-Ho
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Abstract
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Leptospirosis is a spirochaetal infectious disease caused by Leptospira interrogans. Multiple organ involvement may be encountered in leptospirosis. Early renal involvement is very common and aracterized by tubulo-interstitial nephritis and tubular dysfunction. Rarely, diffuse mesangial proliferative glomerulonephritis may be seen. Immunoglobulin A nephropathy (IgA nephropathy) is defined by the
predominant deposition of IgA in the glomerular mesangium. The secondary IgA nephropathy is thought to be caused by hepatobiliary disease, mucosal disease, infection, malignancy, some hematologic disease and systemic autoimmune or hypersensitivity disease. However, there are few reports about IgA nephropathy associated with leptospirosis. We herein report a case of IgA nephropathy in 21-yearold
leptospirosis patient.
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KEYWORD
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Leptospirosis, IgA nephropathy, Glomerulonephritis
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